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Titlebook: Short-Term Tests for Chemical Carcinogens; H. F. Stich (Head),R. H. C. San (Chief) Conference proceedings 1981 Springer-Verlag New York In

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Induction and Genetic Characterization of Specific Locus Mutations in the , Region in Two-Component Many assay systems have been developed which seem especially well suited for use in mass-screening programs where the objective is to screen large numbers of unknowns and to identify those chemicals with carcinogenic and mutagenic potential. The . forward mutation test system is not suitable for such use.
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978-1-4612-5849-0Springer-Verlag New York Inc. 1981
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https://doi.org/10.1007/978-1-4612-5847-6Calcium; DNA; Krebserregender Stoff; Mutagene; Mutation; Nucleotide
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The Yeast ,: An Assay Organism for Environmental Mutagense study of the cells of higher organisms. Yeast is a true eukaryote, well understood genetically, with both haploid and diploid cell cycles. Meiosis takes place in the diploid cell without the prior differentiation of elaborate fruiting bodies or other sexual paraphernalia.
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The , Mutagenicity Test: An Overview and the effect of additions to the “S9 mix”such as antioxidants, EDTA, or enzyme inhibitors, can easily be investigated. In addition, the test has been used to help isolate and identify mutagens present in complex mixtures, to study the effect of comutagens, and as an adjunct in the development of useful, non-mutagenic chemicals.
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