Titlebook: Serotonin and Sleep: Molecular, Functional and Clinical Aspects; Jaime M. Monti,S. R. Pandi-Perumal,David J. Nutt Book 2008 Birkhäuser Bas

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Jaime M. Monti,S. R. Pandi-Perumal,David J. NuttOverview of current approaches and medications.Up-to-date reference resource.Interesting and readable.Includes supplementary material:

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Birkhäuser Basel 2008

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Changing concepts on the role of serotonin in the regulation of sleep and wakingin EEG synchronization. In parallel, the areas of sleep research and neurochemistry have seen enormous developments. The concept of serotonin as a sleep neurotransmitter was based on the effects of lesions of the brainstem raphe nuclei and the effects of serotonin depleting drugs in cats. The descri

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Topographic organization and chemoarchitecture of the dorsal raphe nucleus and the median raphe nuclbrain region involved. Increasing evidence points toward the existence of multiple topographically organized subpopulations of serotonergic neurons that receive unique afferent connections, give rise to unique patterns of projections to forebrain systems, and have unique functional properties. A bet

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Reciprocal connections between the suprachiasmatic nucleus and the midbrain raphe nuclei: A putativeall mammalian behaviors and physiological processes, including sleep and wakefulness. Serotonergic neurons in the midbrain dorsal (DRN) and median (MRN) raphe nuclei have been suggested to play an important role in behavioral state control. These neurons also show circadian rhythmicity in their acti

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Localization of 5-HT receptors in the mammalian cortexological functions, including sleep. Derangements of the serotonergic system are suspected in several psychiatric disorders, including mood and anxiety disorders. A large body of data supports a prominent role of dopamine in cortical function. However, much less is known on the role of serotonin (5-

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