| 书目名称 | Serotonin and Sleep: Molecular, Functional and Clinical Aspects | | 编辑 | Jaime M. Monti,S. R. Pandi-Perumal,David J. Nutt | | 视频video | | | 概述 | Overview of current approaches and medications.Up-to-date reference resource.Interesting and readable.Includes supplementary material: | | 图书封面 |  | | 描述 | Foreword Barry Jacobs once memorably commented that the problem in understanding the role of serotonin in the brain was that it was implicated in virtually eve- thing but responsible for nothing [1]. Serotonin (5-HT) is defnitely implicated in the regulation of sleep but what does it do? Once seen as a sleep-promoting molecule, Jacob’s own work, lucidly described in this volume, radically changed our view. In fact, serotonin neurons are most active during waking; their - tivity diminishes with sleep onset and disappears during rapid eye movement (REM) sleep. Serotonin, therefore, is intimately linked to the sleep-wake cycle, but what is its role, what mechanisms are involved and what are the impli- tions for sleep medicine and psychiatry? Making progress with these diffcult questions requires a “translational” approach, which is a research paradigm where both laboratory and clinical neuroscience inform and guide each other with the ultimate aim of improving understanding and treatment of medical conditions. This volume is a superb example of translational research, where leading basic and clinical scientists - tegrate molecular, neuropharmacological and systems approaches to illumi | | 出版日期 | Book 2008 | | 关键词 | Arousal; Nervous System; biology; brain; central nervous system; cortex; evolution; molecular biology; neuro | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-7643-8561-3 | | isbn_ebook | 978-3-7643-8561-3 | | copyright | Birkhäuser Basel 2008 |
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发表于 2025-3-21 16:50:46
