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Titlebook: Serotonin and Sleep: Molecular, Functional and Clinical Aspects; Jaime M. Monti,S. R. Pandi-Perumal,David J. Nutt Book 2008 Birkhäuser Bas

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Reciprocal connections between the suprachiasmatic nucleus and the midbrain raphe nuclei: A putative the medial preoptic area, subparaventricular zone, and dorsomedial hypothalamic nucleus. We discuss functional evidence to suggest that the SCN may influence the regulation of sleep-wake states by sending its circadian signal through these indirect pathways to the raphe nuclei. We then consider the
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Brain serotonergic neuronal activity in behaving catsher, often dramatic, activation is seen in association with repetitive, central motor program-mediated behaviors (e.g., feeding, licking, respiration, and locomotion). The exact nature of this relationship varies both with the serotonergic neuronal group (e.g., locomotor-related medullary neuronal a
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Electrophysiological studies on serotonergic neurons and sleep neurons are evenly distributed in the DRN, and their activity is related to the level of behavioral arousal, as they discharge regularly at a high rate during waking (W) and at progressively slower rates during SWS, and cease firing during SWS with ponto-geniculo-occipital waves and PS (type I-A) o
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Regulation of serotonin release by inhibitory and excitatory amino acids the excitatory influence of glutamatergic inputs to serotonergic neurons in the DRN. Peptidergic neurons modulate the activity of GABAergic and glutamatergic interneurons that synapse with serotonergic neurons in the DRN. These neuropeptides, for example CRF, endogenous opioids and Substance P, are
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