Titlebook: Selective Activation of Drugs by Redox Processes; G. E. Adams,A. Breccia,P. Wardman Book 1990 Plenum Press, New York 1990 cancer.chemother

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Activity of Bioreductive Agents in Human and Rodent Tumor Cells,ancer agents. because (i) these cells may be relatively inaccessible to the drug because they are located in poorly vascularized areas of a tumor, (ii) hypoxia . may reduce the efficacy of the agent, or (iii) under hypoxic conditions cells may be in a non-cycling state which protects them from cycle specific drugs.

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Reduction of Bleomycin-Fe by Reductases and Active Oxygen Formation,tases present in intact cell nuclei are able to catalyze the reduction of bleomycin-Fe(III), the formation of active oxygen and the oxidative cleavage of nuclear DNA. This is important, because DNA damage catalyzed by nuclear reductases may be directly related to cell toxicity induced by bleomycin.

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aerodynamics capability: the Doublet Lattice Method.Theoreti.Aeroelasticity is an essential discipline for the design of airplanes, unmanned systems, and innovative configurations...This book introduces the subject of unsteady aerodynamics and dynamic aeroelasticity by presenting industry-standard t

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Peter Wardmanject of unsteady aerodynamics and dynamic aeroelasticity by presenting industry-standard techniques, such as the Doublet Lattice Method for nonplanar wing systems. “.Introduction to Unsteady Aerodynamics and Dynamic Aeroelasticity.‘‘ is a useful reference for aerospace engineers and users of NASTRAN

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Petr Zumanject of unsteady aerodynamics and dynamic aeroelasticity by presenting industry-standard techniques, such as the Doublet Lattice Method for nonplanar wing systems. “.Introduction to Unsteady Aerodynamics and Dynamic Aeroelasticity.‘‘ is a useful reference for aerospace engineers and users of NASTRAN

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F. Busiaerodynamics capability: the Doublet Lattice Method.Theoreti.Aeroelasticity is an essential discipline for the design of airplanes, unmanned systems, and innovative configurations...This book introduces the subject of unsteady aerodynamics and dynamic aeroelasticity by presenting industry-standard t