Titlebook: STEM Teachers and Teaching in the Digital Era; Professional Expecta Yifat Ben-David Kolikant,Dragana Martinovic,Marina Book 2020 Springer N

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tlines that epigenetic programming is a learning process that results in epigenetic memory in each of the cells of our body. The central importance of epigenetics during embryogenesis and cellular differentiation as well as in the process of aging and the risk for the development of cancer are discu

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s degree of methylation (mono-, di- or tri-methylation) is critical. The genome-wide view indicates that chromatin modifiers of antagonizing activity frequently co-localize to common genomic loci and mutually fine-tune each other in the control of active, poised and silent genes. The importance of a

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Ruth Waldman,Ron Blonderigenesis process. In pre-malignant cells these epigenetic dys-regulations promote tumor initiation and in malignant cells they accelerate tumor evolution and adaptation. The effects of diverse oncogenic stimuli are mediated via epigenetic modulators and contribute to diverse aspects of cancer biolog

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Ofra Brandes,Yifat Ben-David Kolikant,Catriel Beerimay explain the missing genetic heritability of the susceptibility for complex diseases, such as T2D..In this chapter, we will define different epigenetic mechanisms that process information provided by dietary molecules. We will learn that many chromatin-modifies are susceptible to changes in the l

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Smadar Levy,Esther Bagno,Hana Berger,Bat-Sheva Eylon, referred to as the histone code, that mark genomic regions and pass information to chromatin modifiers and other nuclear proteins. The collection of histone modification patterns from various human cell lines and primary tissues, as provided by ENCODE, Roadmap Epigenomics and IHEC, provide a genom

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Dragana Martinovic,Marina Milner-Bolotinn safety-critical systems; .–Observational studies of safety-critical systems; .–Risk assessment techniques for interactive systems; .–Safety-related interface design, development and testing; .–Formal description techniques for the design and development of safety-critical interactive systems..Many

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