| 书目名称 | Ribosome Biogenesis |
| 副标题 | Methods and Protocol |
| 编辑 | Karl-Dieter Entian |
| 视频video | |
| 概述 | This book is open access, which means that you have free and unlimited access.Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key n |
| 丛书名称 | Methods in Molecular Biology |
| 图书封面 |  |
| 描述 | This Open Access volume provides comprehensive reviews and describes the latest techniques to study eukaryotic ribosome biogenesis. For more than 50 years ribosomes are a major research topic. Our knowledge about ribosome biogenesis and function such as transcription, mRNA modification, and translation was the sine qua non for developing the powerful RNA-based vaccines against RNA-viruses causing the world-threatening Covid-19 pandemia. The chapters in this book are organized into six parts. Part One discusses a comparative survey about the unity and diversity of ribosome biogenesis in pro- and eukaryotic cells. Part Two deals with the genomic organization of eukaryotic rDNA and the role of RNA polymerase I in ribosomal RNA transcription. Part Three explores in vitro methods to study RNA polymerase I structure and its function, and Part Four analyzes the nucleo-cytoplasmic transport of assembled ribosomes and RNP complexes. Part Five covers modifications that increasethe complexity of rRNAs, and Part Six provides readers with a review of eukaryotic translation and - for the first time - describes a new method to analyze translation in vitro. Written in the highly successful .Meth |
| 出版日期 | Book‘‘‘‘‘‘‘‘ 2022 |
| 关键词 | cryo-electron microscopy; ribosome biogenesis; subtunit protein composition; eukaryotes; maturation; Open |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-1-0716-2501-9 |
| isbn_softcover | 978-1-0716-2503-3 |
| isbn_ebook | 978-1-0716-2501-9Series ISSN 1064-3745 Series E-ISSN 1940-6029 |
| issn_series | 1064-3745 |
| copyright | The Editor(s) (if applicable) and The Author(s) 2022 |
发表于 2025-3-21 16:10:21
