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Titlebook: RNA Therapeutics; Function, Design, an Mouldy Sioud Book 2010 Humana Press 2010 DNA.Microarray.PCR.Transplantat.Tumor.cloning.gene expressi

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Effective Pol III-Expressed Long Hairpin RNAs Targeted to Multiple Unique Sites of HIV-1, mutants, however, is a major impediment to the use of RNAi effectors to treat highly mutable viruses such as HIV-1. A combinatorial approach is therefore required for long-term inhibition of gene expression. RNA Pol III-driven long hairpin RNA (lhRNA) duplexes can be cleaved several times by Dicer,
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Profiling of miRNA Expression and Prediction of Target Genes, of human genes, thus underlying their influence on almost all cellular pathways. Recent studies have shown miRNAs to be differentially expressed in cancers. Furthermore, several miRNAs are associated with fragile sites, preferential sites of translation, deletion and amplification that are often al
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