Titlebook: Organ-Selective Actions of Steroid Hormones; D. T. Baird,G. Schütz,R. Krattenmacher Conference proceedings 1995 Springer-Verlag Berlin Hei

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Organ-Selective Actions of Tamoxifen and Other Partial Antiestrogens,ures, indicating that estrogen deficiency alone is insufficient to fully account for the disorder. An increased understanding of the mechanisms whereby estrogen interacts with other factors to maintain bone balance is an important step in improving hormone replacement therapy in postmenopausal women.

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Androgen Action on the Bone, lose about 30% of their trabecular bone and 20% of their cortical bone. Thus, even though osteoporosis is less common in men than in women, one fifth of all hip fractures occur in men and by the age of 90 one of every six men will have fractured his hip.

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Conference proceedings 1995h the goal of attaining a better understanding of the underlying mechanisms of organ selective actions of steroids. Discussed is the extent to which tissue specificity might selectively be modified by chemical modification of the hormones and how this may be applied towards improved therapies by taking advantage of tissue selectivity.

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0947-6075 y has opened the way for more detailed investigation of the complex set of intracellular interactions contributing to organ-selective actions of steroids and steroid-like compounds such as vitamin D. In this volume leading experts address basic molecular mechanisms of tissue specificity and related

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Conference proceedings 1995ed the way for more detailed investigation of the complex set of intracellular interactions contributing to organ-selective actions of steroids and steroid-like compounds such as vitamin D. In this volume leading experts address basic molecular mechanisms of tissue specificity and related issue, wit

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Organ-Selective Actions of Steroid Hormones978-3-662-09153-1Series ISSN 0947-6075

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https://doi.org/10.1007/978-3-662-09153-1Gewebe; Hormone replacement therapy; Hormontherapie; Osteoporose; Promoter; Steroide; Tissue specificity; V

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Development of Tissue-Selective Estrogen Receptor Modulators,roductive function (Clark and Peck 1979). In pathological states, estrogen is also involved in the maintenance and progression of cancers (Sunderland and Osborne 1991) and is implicated in the abnormalities of uterine function observed in endometriosis and possibly uterine fibroids (Kettel et al. 19