Titlebook: Organ-Selective Actions of Steroid Hormones; D. T. Baird,G. Schütz,R. Krattenmacher Conference proceedings 1995 Springer-Verlag Berlin Hei

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Estrogen-Receptor and Antiestrogen-Receptor Complexes: Cell- and Promoter-Specific Effects and Inteuding bone, liver, and the cardiovascular system. Most of the actions of estrogens appear to be exerted via the estrogen receptor (ER) of target cells, an intracellular receptor that is a member of a large superfamily of proteins that function as ligand-activated transcription factors, regulating th

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Androgen Action on the Bone,ely 1.5 million fractures each year (Finkelstein 1995). The annual cost of health care and lost productivity attributed to osteoporosis exceeds $10 billion in the United States. During the course of their lifetimes, women lose about 50% of their trabecular bone and 30% of the cortical bone while men

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General Principles of Vitamin D Action and Mechanism-Based Search for Analogs with Specific Actionsa 1974, 1988). First, 25-hydroxylation is carried out in the microsomes and mitochondria of liver to produce the circulating form of vitamin D 25-hydroxyvitamin D. (25-OH-D.). Secondly, 1α-hydroxylation produces the final hormonal or active form 1,25-dihydroxyvitamin D. (1,25-(OH).D.). In normal hum

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Eldar Fischer,Orly Yahalomions from many eminent specialists across a variety of disciAssessment of human casualties in earthquakes has become a topic of vital importance for national and urban authorities responsible for emergency provision, for the development of mitigation strategies and for the development of adequate in

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Victoria Buchholz,Stefan Kopp diesem Satze Turgenjew’s giebt bie „formale Bildung“ ein Beispiel. Das Wort ist ein Gespenst geworden, mit dem man die erwachsensten Menschen erschreckt. Wer das Gymnasium schelten will, der wirft ihm vor, daß es nichts weiter schaffe als formale Bildung; wer es vertheidigen will, der sucht sich vo