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Titlebook: Organ-Selective Actions of Steroid Hormones; D. T. Baird,G. Schütz,R. Krattenmacher Conference proceedings 1995 Springer-Verlag Berlin Hei

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书目名称Organ-Selective Actions of Steroid Hormones
编辑D. T. Baird,G. Schütz,R. Krattenmacher
视频video
丛书名称Ernst Schering Foundation Symposium Proceedings
图书封面Titlebook: Organ-Selective Actions of Steroid Hormones;  D. T. Baird,G. Schütz,R. Krattenmacher Conference proceedings 1995 Springer-Verlag Berlin Hei
描述Steroids regulate differentiation, growth and functioning of many tissues via a nuclear receptor gene activation mechanism. Molecular biology has opened the way for more detailed investigation of the complex set of intracellular interactions contributing to organ-selective actions of steroids and steroid-like compounds such as vitamin D. In this volume leading experts address basic molecular mechanisms of tissue specificity and related issue, with the goal of attaining a better understanding of the underlying mechanisms of organ selective actions of steroids. Discussed is the extent to which tissue specificity might selectively be modified by chemical modification of the hormones and how this may be applied towards improved therapies by taking advantage of tissue selectivity.
出版日期Conference proceedings 1995
关键词Gewebe; Hormone replacement therapy; Hormontherapie; Osteoporose; Promoter; Steroide; Tissue specificity; V
版次1
doihttps://doi.org/10.1007/978-3-662-09153-1
isbn_softcover978-3-662-09155-5
isbn_ebook978-3-662-09153-1Series ISSN 0947-6075
issn_series 0947-6075
copyrightSpringer-Verlag Berlin Heidelberg 1995
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Estrogen-Receptor and Antiestrogen-Receptor Complexes: Cell- and Promoter-Specific Effects and Inte to effectively activate gene transcription (Jordan and Murphy 1990; Katzenellenbogen et al. 1985; Santen et al. 1990). Two of the major challenges in studies on antiestrogens are to understand what accounts for their antagonistic effectiveness, as well as the partial agonistic effects of some antie
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Organ-Specific Actions of Vitamin D Analogs: Relevance of Rapid Effects,considerable attention of late is its ability to stimulate rapid actions in target cells. These rapid actions include stimulation of lipid turnover (Lieberherr et al. 1989; DeBoland and Boland 1993), Ca. influx via plasma membrane voltage-sensitive Ca. channels (Caffrey and Farach-Carson 1989; DeBol
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R. L. Sutherland,C. S. L. Lee,A. L. Cornish,E. A. Musgrove
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