Titlebook: New Concepts in Depression; M. Briley,G. Fillion Textbook 1988Latest edition Macmillan Publishers Limited 1988 clinical research.depressio

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Thyrotrophin-realeasing Hormone (TRH) and 5-Hydroxytryptamine (5-HT) Interactions and Their Involver number and responsiveness. Furthermore, the down-regulation of β-adrenocep-tors produced by antidepressant treatments is dependent upon intact 5-HT neurones. There is, however, little information about the factors involved in the regulation of 5-HT receptor function. This chapter investigates the

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Lithium Augmentation of Antidepressant Treatments: Evidence for the Involvement of the 5-HT System?posed for treatment-resistant depression: reserpine (Poldinger, 1963; Haškovec and Rysánek, 1967; Hopkinson and Kenny, 1975; Zohar .., 1987), T. (Earle, 1969; Ogura .., 1974; Banki, 1977; Goodwin .., 1982), psychostimulants (Wharton ., 1971; Ayd and Zohar, 1987), oestrogen supplementation (Shapira .

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