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Titlebook: New Concepts in Depression; M. Briley,G. Fillion Textbook 1988Latest edition Macmillan Publishers Limited 1988 clinical research.depressio

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,Central and Peripheral Effects of CH-38083: a New α2-Antagonist,a selective antagonist of monoamine oxidase A (MAO-A) (Cohen .., 1982). Desipramine (DMI) produces a short-lasting decrease in the sedation response to α-agonists (Heal .., 1983). The functional response of sedation may involve presynaptic α.-adrenoceptors (see Green and Nutt, 1985): thus DMI exerts
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Contributions from Peripheral Autonomic Pharmacology to an Understanding of Antidepressant Drug Actiprindole, which are not known to directly affect noradrenergic or serotonergic neurons. The clinical effectiveness of agents such as maprotiline and nisoxetine (Iversen and Mackay, 1979), which selectively inhibit neuronal uptake of noradrenaline, points to the importance of the noradrenergic neuro
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Effects of the Membrane-active Antidepressant Drugs, Selective 5-HT or NA Uptake Inhibitors, on ,-C or blockers of 5-HT synthesis, but also by membrane-active drugs such as the antidepressants clomipramine, citalopram and zimelidine which are potent 5 HT uptake inhibitors (Frey, 1975; Pawłowski .., 1980; Pawłowski, 1981). Since clomipramine and citalopram do not prevent the hyperthermia induced b
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A. Coppen,C. Swadecontemporary global culture. In doing this, it has also been shown how unsatisfactory these assumptions are in terms of their logic and their adequacy. Most of them contain logical inconsistencies and all are inadequate in that they do not provide plausible explanations of major features of common e
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