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Titlebook: New Concepts in Depression; M. Briley,G. Fillion Textbook 1988Latest edition Macmillan Publishers Limited 1988 clinical research.depressio

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G. Fillion,S. Dufois,C. Fayolle,M. P. Fillion,P. Oudar,P. Barone
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L. Marlier,F. Finiels-Marlier,P. Poulat,N. Koenig,M.-J. Drian,A. Privat
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Beyond Nosology in Biological Psychiatry. 5-HT Disturbances in Mood, Aggression and Anxiety Disordeecific. Van Kämmen (1987) called 5-HT, ironically, a neurotransmitter of all seasons. We do not concur with either statement and in this chapter we explain why. First we discuss the available data; then we try to bring them into a conceptual framework.
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Lithium Augmentation of Antidepressant Treatments: Evidence for the Involvement of the 5-HT System?tment of choice for resistant depression (Medical Research Council, 1965; Davidson .., 1978). British investigators have recently advanced that lithium addition might soon supersede the use of ECT in treatment-resistant depression (Pai .., 1986).
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,Is Down-regulation of β-Adrenoceptors Necessary for Antidepressant Activity?,s of these compounds are not usually seen until after 2 to 3 weeks of continual treatment. Additionally, so-called ‘atypical’ antidepressants such as mianserin and iprindole appear not to inhibit the metabolism or reuptake of monoamines (see Stone, 1983).
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