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Titlebook: Lessons from Animal Diabetes VI; 75th Anniversary of Eleazar Shafrir Book 1996 Birkhäuser Boston 1996 Diabetes.Diabetes mellitus.genetics.

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Glucose and lipid metabolism in the gold thioglucose injected mouse model of diabesity During toxicology studies, it was noted by Brecher and Waxier. that a single i.p. or s.c. injection of GTG induced a syndrome of hyperphagia and obesity in mice. This observation was subsequently confirmed by Marshall and colleagues,. who reported that GTG induced bilateral necrosis of the ventrome
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Diabetes in the Chinese hamstertment of pneumonia at the Peking Medical College Hospital in 1919 because laboratory mice were not available.. The Chinese or “striped-back” hamster is recognized by the black stripe that runs down the middle of the otherwise yellowish-brown fur on its back. The hamster is also known for its low chr
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Studies on the pathogenesis of NIDDM in the GK (Goto-Kakizaki) ratsues.. It is still a matter of debate as to which of these defects is primary. However, impaired insulin secretion seems to be a prerequisite for the development of NIDDM.. When the B-cells fail to secrete enough insulin to compensate for insulin resistance, hyperglycemia develops. In contrast, subj
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Role of immune and non-immune aspects of genetics in different expressions of diabetes in db/db micedevelopment of novel treatment and prevention strategies. Additional contribution derived from investigation of spontaneous and induced forms of diabetes resembling human IDDM and NIDDM, two entities distinguished by their pathogenic background and their clinical presentation. Among the animal model
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Inositols—Potential roles in insulin action and in diabetes: Evidence from insulin-resistant nonhuma first identified in cardiac muscle by Scherer in 1850. It is a component of membrane phospholipids, and the function of these membrane phosphoinositides may prove to be important to the action of insulin, as discussed later. Myoinositol, a cyclitol, is the most common of the nine isomers of hexahyd
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