Titlebook: Immuno-Psychiatry; Facts and Prospects Michael Berk,Marion Leboyer,Iris E. Sommer Book 2021 Springer Nature Switzerland AG 2021 Immunology.

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Microglia and Psychiatric Disorders so, we present evidence from human genetics, . tissue studies, epidemiological studies and in vivo positron emission tomography (PET) imaging. In addition, we consider how functional changes in microglia could lead to psychiatric disorders, with a particular focus on the putative role of microglia

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Human Endogenous Retrovirus as Missing Link in the Global Etiopathogenesis of Schizophrenia and BipoERV-W ENV inhibited HERV-W ENV pathogenic effects in vitro and prevented abnormal behavioral signs in vivo. A lifelong scenario of interactions between environmental pathogens and HERV-W genes is now presented, which may decipher the actual development and course of such diseases. New therapeutic st

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Gut Microbiome in Patients with Schizophrenia and Bipolar Disorderdicate that there are differences in the microbiome in schizophrenia and bipolar disorder patients as compared with healthy controls. Part of these differences may be induced by medication use, others by smoking and other lifestyle factors. Correlations between microbiome quantification and symptom

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The Aberrant Immune System in Bipolar Disorderillness progression, via alterations in the tryptophan catabolism and via dysfunction of glial cells, such as the microglia and oligodendrocytes. Therapeutic immune interventions in BD have thus far mainly been focused on non-steroidal anti-inflammatory drugs (NSAID), omega-3-fatty acids, and N-acet

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Inflammation and Depression: Is Immunometabolism the Missing Link?of immune cells and their production of immune communication signals influence their function. We will then examine how this metabolic reprogramming taking place at the periphery and in the brain because of the propagation of the immune response from the periphery to the brain might interfere with b

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