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Titlebook: Genotoxicity and DNA Repair; A Practical Approach L. María Sierra,Isabel Gaivão Book 2014 Springer Science+Business Media New York 2014 DNA

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https://doi.org/10.1007/978-3-642-91523-9preparation of mouse metaphase cells for whole chromosome FISH analysis. Also presented are basic recommendations on how to visualize the slides and how to organize the data for analysis and interpretation.
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https://doi.org/10.1007/978-3-662-39472-4 action (MOA) of the test substance. This chapter provides up-to-date methodology for carrying out the assay in different cell lines in the presence and absence of metabolism with relevant technical information and emerging advances in statistical analysis of data generated from the HPRT gene mutation assay.
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https://doi.org/10.1007/978-3-662-05530-4limitations, both experimental and biological, is essential to improve both data quality and data relevance obtained and to guarantee that comet assay continues to provide enhanced reliability as a biomarker in human biomonitoring studies.
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Chromosomal Aberration Test Utilities In Vitro and In Vivoons that can exercise their mutagenic potential, and their action mechanism. This chapter discusses the history of CA formation and some cytogenetic protocols that may be used to perform the chromosomal aberration test in in vivo and in vitro studies.
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The Applicable Use of the HPRT Gene Mutation Assay as a Practical Tool in Mutagenesis and DNA Repair action (MOA) of the test substance. This chapter provides up-to-date methodology for carrying out the assay in different cell lines in the presence and absence of metabolism with relevant technical information and emerging advances in statistical analysis of data generated from the HPRT gene mutation assay.
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The Comet Assay In Vivo in Humanslimitations, both experimental and biological, is essential to improve both data quality and data relevance obtained and to guarantee that comet assay continues to provide enhanced reliability as a biomarker in human biomonitoring studies.
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