| 书目名称 | Genotoxicity and DNA Repair |
| 副标题 | A Practical Approach |
| 编辑 | L. María Sierra,Isabel Gaivão |
| 视频video | |
| 概述 | Focuses on key assays in genotoxicity and DNA repair.Places special emphasis on the analysis of nanoparticles and nanomaterials.Features reproducible techniques and expert implementation advice.Includ |
| 丛书名称 | Methods in Pharmacology and Toxicology |
| 图书封面 |  |
| 描述 | .Genotoxicity and DNA Repair: A Practical Approach. provides a key reference for determining how to analyze the genotoxic activity of molecules or materials and, at the same time, serves as a useful tool for researchers in the Environmental Mutagenesis and DNA Repair fields. Focused on genotoxicity assays recommended by the “OECD guidelines for the testing of chemicals”, this volume also covers other useful assays, such as some gene mutation assays, the comet assay in different species and applications, and the SMART assays of Drosophila. For all the assays, the book presents brief theoretical introductions to the topics and updated standard and modified step-by-step protocols to perform them. Special emphasis is placed on the analysis of nanoparticles, including an integrative approach analysis. The DNA Repair section includes several assays that provide information on repair activity in vitro and in vivo, as well as recent applications to study DNA repair in humans, cell cultures, and animal models. As a volume in the .Methods in Pharmacology and Toxicology. series, the chapters contain the kind of detail and key implementation advice that ensures reproducible results in the lab. |
| 出版日期 | Book 2014 |
| 关键词 | DNA repair assays; Environmental mutagenesis; Gene mutation assays; Genotoxic activity; Nanoparticles an |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-1-4939-1068-7 |
| isbn_softcover | 978-1-4939-4829-1 |
| isbn_ebook | 978-1-4939-1068-7Series ISSN 1557-2153 Series E-ISSN 1940-6053 |
| issn_series | 1557-2153 |
| copyright | Springer Science+Business Media New York 2014 |
发表于 2025-3-21 20:00:16
