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Titlebook: Genomics, Personalized Medicine and Oral Disease; Stephen T. Sonis, DMD, DMSc Book 2015 Springer International Publishing Switzerland 2015

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发表于 2025-3-21 17:33:30 | 显示全部楼层 |阅读模式
书目名称Genomics, Personalized Medicine and Oral Disease
编辑Stephen T. Sonis, DMD, DMSc
视频video
概述This book catalyzes the application of genomics to oral diseases by comprehensively presenting focused discussions on the current state of knowledge.Also focuses on gene-based therapies and pharmacoge
图书封面Titlebook: Genomics, Personalized Medicine and Oral Disease;  Stephen T. Sonis, DMD, DMSc Book 2015 Springer International Publishing Switzerland 2015
描述The objective of this book is to catalyze the application of genomics to the diagnosis and treatment of oral diseases by comprehensively presenting focused discussions on the current state of knowledge. The first section book provides basic information about genetics, genomics and personalized medicine and the informatical methods available to apply and organize genetic data so that it has clinical relevance. Recognizing the genetic robustness of the oral cavity, the introductory section includes chapters on the oral micro biome and host genomics and response to infectious agents. The next two sections contain chapters which describe the genomics of specific oral diseases and conditions, including the genetic basis for mechanism and risk of treatment toxicities associated with cancer therapy and bisphosphonates. Four chapters focus on gene-based therapies and the pharmacogenomics applied to oral disease. The final chapter presents a provocative summary which describes a comprehensive vision of the melding of genomics to personalized medicine and the potential actionable outcomes that will likely affect clinical practice in the upcoming years.
出版日期Book 2015
关键词chromosome; genomics; oral disease; personalized medicine; pharmacogenomics
版次1
doihttps://doi.org/10.1007/978-3-319-17942-1
isbn_softcover978-3-319-34737-0
isbn_ebook978-3-319-17942-1
copyrightSpringer International Publishing Switzerland 2015
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Einleitung und Problemstellung,r, our goal is to review the human genetics and genomics literature with an emphasis on the areas that may impact the clinical application of the personalized medicine model for the prevention or treatment of dental caries.
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https://doi.org/10.1007/978-3-662-34637-2ted to a few loci, most importantly .., . and ., which gave evidence of disease relevance by statistically significant associations and replication in large homogenous study populations. These genes are largely located in regulatory networks that integrate interactions of the metabolic and immune sy
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ehensive vision of the melding of genomics to personalized medicine and the potential actionable outcomes that will likely affect clinical practice in the upcoming years.978-3-319-34737-0978-3-319-17942-1
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