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Titlebook: Genetics of Male Infertility; A Case-Based Guide f Mohamed Arafa,Haitham Elbardisi,Ashok Agarwal Book 2020 Springer Nature Switzerland AG 2

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楼主: 刘兴旺
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Quantitative empirische Marktanalyse,pathways underlying male infertility. This chapter reviews these technologies and the discoveries they have led to and sets the scene for the transformation of infertile patient care in the era of next-generation sequencing.
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Sperm DNA Fragmentation and Male Infertilitychapter elucidates the molecular changes, specifically proteomic alterations, caused due to SDF. Moreover, the factors affecting sperm DNA integrity and the consequences of increased SDF are highlighted. It also focusses on the importance of SDF testing and its impact on reproductive outcomes.
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Molecular Regulation of Sperm Production Cascadee implementation of whole genome studies has added more candidates that need further in-depth research for dissecting their biological roles. In this chapter, we have summarized the genes important for spermatogonial stem cell renewal, meiosis, and spermiogenesis and the association of mutations in
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Genetics of Vas Aplasiaon or two mild CFTR mutations. A proportion of CBAVD men (11–20%) suffer from concomitant urogenital abnormalities. CFTR mutations are generally not detected in these men, and other genetic causes are postulated. The type and severity of mutation vary with geography and ethnicity. Current ASRM, ACOG
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