Titlebook: Gene Delivery to Mammalian Cells; Volume 2: Viral Gene William C. Heiser Book 2004 Humana Press 2004

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Recess

Adenovirus-Mediated Gene Delivery to Dendritic Cells to mount a specific cellular and humoral response. Recognition of this crucial function makes the development of technologies for DC-based immuno-therapies a priority for the treatment of a wide variety of diseases. The most immediate impact of this emerging technology will be in the treatment of c

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Overview of Adeno-Associated Viral Vectorsticularly useful for applications where sustained gene expression is required. Prolonged in vivo expression following A AV treatment has been seen in the liver (.,.), brain (.,.), skeletal muscle (.,.), lung (.,.), and hematopoietic stem cells (.,.) of animal models. Therapeutic benefit from A AV tr

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AAV Vector Delivery to Cells in Cultureuman diseases. AAV’s inability to self-propagate, ability to be maintained as an episome in the transduced cell, and relatively innocuous effects on the immune system make it the vector of choice for prolonged in vivo gene expression. AAV type 2 is the most commonly used serotype for gene delivery.

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