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Titlebook: Gene Delivery to Mammalian Cells; Volume 2: Viral Gene William C. Heiser Book 2004 Humana Press 2004

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书目名称Gene Delivery to Mammalian Cells
副标题Volume 2: Viral Gene
编辑William C. Heiser
视频video
概述Includes supplementary material:
丛书名称Methods in Molecular Biology
图书封面Titlebook: Gene Delivery to Mammalian Cells; Volume 2: Viral Gene William C. Heiser Book 2004 Humana Press 2004
描述The efficiency of delivering DNA into mammalian cells has increased t- mendously since DEAE dextran was first shown to be capable of enhancing transfer of RNA into mammalian cells in culture. Not only have other chemical methods been developed and refined, but also very efficient physical and viral delivery methods have been established. The technique of introducing DNA into cells has developed from transfecting tissue culture cells to delivering DNA to specific cell types and organs in vivo. Moreover, two important areas of biology—assessment of gene function and gene therapy—require succe- ful DNA delivery to cells, driving the practical need to increase the efficiency and efficacy of gene transfer both in vitro and in vivo. TM These two volumes of the Methods in Molecular Biology series, Gene Del- ery to Mammalian Cells, are designed as a compendium of those techniques that have proven most useful in the expanding field of gene transfer in mammalian cells. It is intended that these volumes will provide a thorough background on chemical, physical, and viral methods of gene delivery, a synopsis of the myriad techniques currently available to introduce genes into mammalian cells, a
出版日期Book 2004
版次1
doihttps://doi.org/10.1385/1592596509
isbn_softcover978-1-61737-353-4
isbn_ebook978-1-59259-650-8Series ISSN 1064-3745 Series E-ISSN 1940-6029
issn_series 1064-3745
copyrightHumana Press 2004
The information of publication is updating

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Professional Response to Child Sexual Abuse vivo is now the milestone for gene therapy to succeed against disseminated cancer. Therefore, most valuable information is obtained from studies of vector biodistribution. Owing to the hepatotropism of adenoviral vectors, a particularly important parameter is the tumor/liver ratio. This ratio can b
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https://doi.org/10.1007/978-1-349-19270-0 to mount a specific cellular and humoral response. Recognition of this crucial function makes the development of technologies for DC-based immuno-therapies a priority for the treatment of a wide variety of diseases. The most immediate impact of this emerging technology will be in the treatment of c
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Geetanjali Gangoli,Marianne Hesterticularly useful for applications where sustained gene expression is required. Prolonged in vivo expression following A AV treatment has been seen in the liver (.,.), brain (.,.), skeletal muscle (.,.), lung (.,.), and hematopoietic stem cells (.,.) of animal models. Therapeutic benefit from A AV tr
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