Titlebook: Gene Delivery; Huayu Tian,Xuesi Chen Reference work 2022 Springer Nature Singapore Pte Ltd. 2022 Gene carriers.Gene therapy.Antitumor.Gene

VOC

Bioinspired Fabrication of Peptide-Based Capsid-Like Nanoparticles for Gene Delivery,noparticles have capsid-like nanostructures, ordered secondary structures and biofunctions for molecular delivery. CLNs are capable of serving as biocompatible, biosafety, and efficient gene vectors. The following section will describe the typical protocols for fabricating the peptide-based capsid-like nanoparticles for gene delivery.

别炫耀

transient-pain

Dedication

行为

恃强凌弱

Blood-Vessels

https://doi.org/10.1007/978-1-4842-1931-7te the mucus layer due to the adsorption of mucin glycoproteins that trap and destabilize the polyplexes. In this study, a series of fluorinated cationic polypeptides were constructed based on ring-opening polymerization and click chemistry, aiming to synchronize mucus permeation and cell penetratio

Glutinous

https://doi.org/10.1007/978-1-4842-7866-6ecules to the cytoplasm of target cells still remains a huge challenge for the application in vivo. Here, this protocol describes a practical approach to prepare a highly flexible polymeric hybrid micelles for the in vivo delivery of siRNA. The micelles consist of cationic polycaprolactone-polyethyl

不近人情

,‘Walking in the middle of the road’,cy. In recent years, the development of nonviral gene carriers has received great interest worldwide. However, the limitations of safety and low therapeutic efficacy make few nonviral gene vectors be used in clinical therapy of cancer. Therefore, co-delivery of functional genes and chemotherapeutic

urethritis

https://doi.org/10.1007/978-94-015-0491-1ication. The present protocol focuses on synthesis, preparation, characterization of the gene carriers, including gene transfection efficiency evaluation as well as intracellular tracking. The synthesis of dendritic lipopeptides with bio-reducible disulfide linkage and dual aliphatic chains was firs