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Titlebook: Gene Delivery; Huayu Tian,Xuesi Chen Reference work 2022 Springer Nature Singapore Pte Ltd. 2022 Gene carriers.Gene therapy.Antitumor.Gene

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书目名称Gene Delivery
编辑Huayu Tian,Xuesi Chen
视频video
概述Serves as an everyday reference for scientists, practitioners and students in gene delivery.Presents recent developments of nanoparticles for clinical gene therapy.Employs a systematic approach offeri
丛书名称Biomaterial Engineering
图书封面Titlebook: Gene Delivery;  Huayu Tian,Xuesi Chen Reference work 2022 Springer Nature Singapore Pte Ltd. 2022 Gene carriers.Gene therapy.Antitumor.Gene
描述Gene therapy has been regarded as a great potential for specific treatment of gene-related human diseases, such as cancer, genetic and epidemic diseases. Gene therapy refers to the biomedical technology that inserts normal or therapeutic exogenous genes into target cells to repair or replace defective genes in target cells, so as to achieve the purpose of treating diseases. Efficient gene delivery systems are the crucial roles for successful implementation of gene therapy. This book provides a platform for young scholars and students to systematically understand the preparation and characterization of the existing non-viral gene delivery systems, as well as providing a technology platform for clinical gene therapy.
出版日期Reference work 2022
关键词Gene carriers; Gene therapy; Antitumor; Gene editing; Cationic polymers
版次1
doihttps://doi.org/10.1007/978-981-16-5419-0
isbn_ebook978-981-16-5419-0Series ISSN 2523-8809 Series E-ISSN 2523-8817
issn_series 2523-8809
copyrightSpringer Nature Singapore Pte Ltd. 2022
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Pulmonary Co-delivery of DOX and siRNA,RNA complex nanoparticles were obviously smaller and fewer in numbers than mice treated with DOX or siRNA alone, which could be due to the synergistic antitumor effects of DOX and siRNA. Furthermore, most DOX and siRNA were found in the tumor of lungs after pulmonary administration, but rarely restr
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,Fluorinated α-Helical Polypeptides Toward Pulmonary siRNA Delivery,in vivo anti-inflammatory results indicated that the P3F16/siTNF-α and P7F7/siTNF-α polyplexes can significantly reduce the expression of pro-inflammatory factors, such as TNF-α and IL-6. It thus renders promising potentials toward the treatment of pulmonary diseases via noninvasive, localized deliv
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Preparation and Evaluation of Polymeric Hybrid Micelles to Co-deliver Small Molecule Drug and siRNAn. In order to efficiently block the key inflammatory signaling NF-κB pathway in rheumatoid arthritis (RA), siRNA targeting p65 (a key subunit of NF-κB family) combined with small molecule drugs dexamethasone (Dex) using the hybrid micelle as a carrier has been developed for the treatment of RA. The
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Preparation and Application of MPEG-PCL-g-PEI Cationic Micelles in Cancer Therapy,lation time, targeting to tumor tissue via enhanced permeability and retention effect. In this regard, this protocol focuses on the functional gene and chemotherapeutic drug co-delivery cationic micelles used in cancer therapy. Here, the preparation and characterization of gene and drug co-delivery
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