Titlebook: Gene Delivery; Huayu Tian,Xuesi Chen Reference work 2022 Springer Nature Singapore Pte Ltd. 2022 Gene carriers.Gene therapy.Antitumor.Gene

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Yvonne Winfildah Takawira-Matwaya-PBA) via electrostatic interaction. The results demonstrated that PEGylated polymer shell significantly reduces nonspecific interaction at physiological condition. Furthermore, MDNP is capable of detaching polymer shell at tumor acidic microenvironment, facilitating the cellular internalization and

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Fred M. Ssewamala,Ozge Sensoy Baharilic MPEG-PCL-PEI (PPP) tri-block cationic polymer have been designed to deliver Nur77/ΔDBD gene with high transfection efficiency, which consisted of methoxy-poly(ethylene glycol) (MPEG), polycaprolactone (PCL), and positively charged polyethyleneimine (PEI). In order to further maintain long-lasti

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https://doi.org/10.1007/978-1-349-15827-0The miRNA- and SPIO-encapsulating micelle was named T-PBP@miRNA/SPIO which specifically delivered the miRNA-29b and miRNA-122 into the HSCs in an MRI-monitorable manner, leading to a synergistic anti-fibrosis outcome via the downregulation of pro-fibrotic protein such as collagen I (COL1A1), .-smoot

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Jérôme Ballet,Benoit Lallau,Claudine Dumbi nanomicelle for co-delivery of drug/gene. The co-delivery system of chemotherapy drugs (docetaxel, DTX) and siRNA (siRNA-Bcl-2) obviously reduced the expression of antiapoptotic Bcl-2 gene and synergistically promoted antitumor activity of DTX. The present results demonstrate that the polypeptide c

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Reference work 2022ementation of gene therapy. This book provides a platform for young scholars and students to systematically understand the preparation and characterization of the existing non-viral gene delivery systems, as well as providing a technology platform for clinical gene therapy.

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