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L-Asparaginase in the Treatment of Neoplastic Diseases of the Dog, Cat and Cow] and are predominantly of lymphatic or hematopoeitic origin. Rarely, other tumor types, including a rat fibrosarcoma [8], a mouse mammary carcinoma [15], and two cases of human malignant melanoma [6, 12] may be suppressed by treatment with asparaginase.
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https://doi.org/10.1007/978-3-663-19800-0bjected to isoelectric focusing, a procedure which separates compounds through a pH gradient according to their isoelectric point regardless of molecular size. Suprisingly, very different patterns of activity were obtained (Fig. 1).
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