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Titlebook: Excipient Applications in Formulation Design and Drug Delivery; Ajit S Narang,Sai H S. Boddu Book 2015 Springer International Publishing S

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Gerald Kapp,David Butler Manning Recent developments in the understanding of degradation pathways further impact methodologies used in the pharmaceutical industry for prospective stability assessment. This paper discusses these emerging aspects in terms of limitations of drug-excipient compatibility studies, emerging paradigms in
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Advances in Global Change Research degradation at the site of absorption plays a role in determining its bioavailability. Nonetheless, a mechanistic understanding of drug-excipient interactions and their impact on drug release and absorption can help develop formulations that exhibit optimum drug bioavailability.
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https://doi.org/10.1007/978-3-642-75211-7r physicochemical characteristics, and increasing their stability. In this chapter, we focus primarily on the factors determining and influencing bioavailability as well as the selection of excipients for formulating new dosage forms with enhanced therapeutic efficacy, based on the physicochemical p
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https://doi.org/10.1007/978-3-322-95714-6a barrier coating to reduce rate and extent of moisture ingress into the core of the solid dosage form during the storage (in original packaging or while in-use), are some of the many simple options that have been considered and described.
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https://doi.org/10.1007/978-1-4302-4051-8ducts. Similarly, in topical drug delivery applications, silicone based novel excipients have demonstrated their capability in improving drug delivery efficiency. Recent silicone technologies like swollen crosslinked silicone elastomer blend networks, sugar siloxanes, amphiphilic resin linear polyme
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