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Titlebook: Excipient Applications in Formulation Design and Drug Delivery; Ajit S Narang,Sai H S. Boddu Book 2015 Springer International Publishing S

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书目名称Excipient Applications in Formulation Design and Drug Delivery
编辑Ajit S Narang,Sai H S. Boddu
视频videohttp://file.papertrans.cn/319/318378/318378.mp4
概述Provides an in-depth perspective into a spectrum of excipient focused topics highly relevant to drug development and manufacture.Examines how the functional attributes of excipients affect biological
图书封面Titlebook: Excipient Applications in Formulation Design and Drug Delivery;  Ajit S Narang,Sai H S. Boddu Book 2015 Springer International Publishing S
描述.In recent years, emerging trends in the design and development of drug products have indicated ever greater need for integrated. .characterization of excipients and in-depth understanding of their roles in drug delivery applications. This book presents a concise summary of relevant scientific and mechanistic information that can aid the use of excipients in formulation design and drug delivery applications. Each chapter is contributed by chosen experts in their respective fields, which affords truly in-depth perspective into a spectrum of excipient-focused topics. .This book captures current subjects of interest – with the most up to date research updates – in the field of pharmaceutical excipients. This includes areas of interest to the biopharmaceutical industry users, students, educators, excipient manufacturers, and regulatory bodies alike. .
出版日期Book 2015
关键词amorphous drugs; drug delivery; excipients; generics; impurities
版次1
doihttps://doi.org/10.1007/978-3-319-20206-8
isbn_softcover978-3-319-37107-8
isbn_ebook978-3-319-20206-8
copyrightSpringer International Publishing Switzerland 2015
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Reactive Impurities in Excipientsessing, and their potential reactions with drug candidates are discussed. Specific examples of drug–excipient impurity interaction are presented as illustrative case studies. Mitigation strategies and corrective measures are also discussed.
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Protein—Surfactant Interactions at the Air-Water Interfaceeater than that of Mouse IgG. Degrees of displacement by Triton X-100 were comparable in case of studied proteins. Surface tension characterization suggests that the interfacial interactions between proteins and surfactants are driven not only by their surface activity but also by the network format
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Excipient Selection in Oral Solid Dosage Formulations Containing Moisture Sensitive Drugsa barrier coating to reduce rate and extent of moisture ingress into the core of the solid dosage form during the storage (in original packaging or while in-use), are some of the many simple options that have been considered and described.
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