Titlebook: Drug Targets in Kinetoplastid Parasites; Hemanta K. Majumder Book 2008 The Editor(s) (if applicable) and The Author(s), under exclusive li

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0065-2598 parasites resistant to many of the available drugs is also responsible for the depressing picture of disease persistence and death. Development of commercially available vaccines is still far from reality, though research and trial programs continue. .978-1-4419-2656-2978-0-387-77570-8Series ISSN 0065-2598 Series E-ISSN 2214-8019

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Scaled boundary finite element methodgood reason for optimism that newer compounds with greater potency and improved pharmacokinetic properties might be more efficacious. Data have been published demonstrating synergistic activity of azole drugs with various other compounds, indicating that combination chemotherapy may be an effective

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Arsenite Resistance in Leishmania and Possible Drug Targets,malaria (WHO). Visceral leishmaniasis or kala-azar, caused by Leishmania donovani, is the most fatal form of leishmaniasis afflicting millions of people worldwide. No vaccination is available against leishmaniasis and fast spreading drug resistance in these parasitic organisms is posing a major medi

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Drugs and Transporters in Kinetoplastid Protozoa,es, translocate compounds from one intracellular compartment to another, and take up or export drugs. The combination of molecular cloning, genetic approaches, and the completed genome projects for . have allowed detailed functional analysis of various transporters and predictions about the likely f

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