Titlebook: Death Receptors in Cancer Therapy; Wafik S. El-Deiry Book 2005 Humana Press 2005 TNF.apoptosis.carcinoma.cell.cell death.gene therapy.inte

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Death Receptor Signaling in Embryonic Ectodermal Development,n the absence or presence of sweat gland function—hidrotic ectodermal dysplasia (or Clouston syndrome) and hypohidrotic ectodermal dysplasias (HEDs). Recent studies suggest an important role of signaling via the tumor necrosis factor receptor (TNFR) family in the pathogenesis of hypohidrotic ectoder

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Adaptor Proteins in Death Receptor Signaling,he function of each adaptor, we hope to construct a blueprint of the various signaling channels triggered by death receptors, providing a foundation for further scientific investigations and practical therapeutic designs.

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TRAIL in Cancer Therapy,ignaling by mechanisms that remain poorly understood. Interestingly, a number of recent reports suggest that a key to the success of TRAIL in cancer therapy is to use it in conjunction with chemo- or radiotherapy. Such a concept of combination therapy is gaining ground in eliminating tumors that are

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Expression and Regulation of Death Receptors in Multiple Myeloma and Prostate Carcinoma,on level following genotoxic stress was prevented or attenuated in prostate cancer cells stably expressing a dominant-negative p53 mutant. Of the TNF family members, one that has received much attention recently is Apo2L/TRAIL (Apo2 ligand or TNF-related apoptosis-inducing ligand). Apo2L/TRAIL is un

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