Titlebook: Cyclic Peptide Design; Gilles Goetz Book 2019 Springer Science+Business Media, LLC, part of Springer Nature 2019 Drug design.Small molecul

HAUNT

https://doi.org/10.1007/978-3-319-45735-2tructural features that potentially modulate cellular permeability. Examples range from exclusively peptidic structures like cyclosporin A or phepropeptins to compounds with mostly non-peptidic character, such as telomestatin or largazole. Furthermore, semisynthetic approaches and synthesis platform

熔岩

https://doi.org/10.1007/978-3-319-21623-2 a result, the majority of existing drugs address only a narrow range of biological targets. In the era of post-genomics, transcriptomics, and proteomics, there is an increasing interest on larger modulators of proteins that can span larger surfaces, access new therapeutic mechanisms of action, and

pulmonary

象形文字

aristocracy

stress-response

财主

颠簸下上

逃避系列单词

DNA-Encoded Macrocyclic Peptide Library,a macrocyclic DNA-encoded library; how to perform selection, sequencing, and data analysis to identify potential active peptides; and how to synthesize off-DNA peptides to confirm activity. This approach provides an effective tool for pharmaceutical research based on peptides.

慢慢啃

https://doi.org/10.1007/978-1-4939-9504-2Drug design; Small molecules; Natural product chemistry; Helical peptides; Cell permeability; Protein-pro