Titlebook: Cyclic Peptide Design; Gilles Goetz Book 2019 Springer Science+Business Media, LLC, part of Springer Nature 2019 Drug design.Small molecul

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978-1-4939-9506-6Springer Science+Business Media, LLC, part of Springer Nature 2019

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Cyclic Peptide Design978-1-4939-9504-2Series ISSN 1064-3745 Series E-ISSN 1940-6029

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Digital Sliding-Mode Prediction Controla macrocyclic DNA-encoded library; how to perform selection, sequencing, and data analysis to identify potential active peptides; and how to synthesize off-DNA peptides to confirm activity. This approach provides an effective tool for pharmaceutical research based on peptides.

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https://doi.org/10.1007/978-3-319-21623-2 scaffolds associated with natural products. Here we describe recent efforts toward identification of novel natural cyclopeptides and macrocycles as well as selected medicinal chemistry strategies to increase drug-like properties or further exploration of their activity.

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Digital Sliding-Mode Prediction Control the market for the treatment of postpartum hemorrhage. Many other OT analogs with improved pharmacological properties (e.g., barusiban, Antag III) have been identified. These peptides have been tested in clinical trials and/or used as pharmacological tools. In this chapter, the modifications of the

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