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Titlebook: Connexin Hemichannels; Methods and Protocol Fabio Mammano,Mauricio Retamal Book 2024 The Editor(s) (if applicable) and The Author(s), under

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Frank A. G. den Butter,Marjan W. Hofkesracellular and intracellular regions are quite different. In this chapter, we provide a detailed instruction to perform MD simulations aimed at computationally modeling the permeation of inorganic ions and larger molecules through Cx HCs.
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https://doi.org/10.1007/1-4020-4631-6ls, a human oligodendroglioma cell line that naturally expresses Panx1. We anticipate these refined protocols will significantly contribute to future characterizations of Panx1-based intercellular cell–cell channels across diverse cell types and offer valuable insights into both normal cellular physiology and pathophysiology.
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Yu.H. Israfilov,M.A. Asadov,T.M. Rashidov contribution to understanding the structure–function relationship of connexin HCs. The protocol is also suitable to screen candidate therapeutic compounds to treat connexin-related diseases linked to HC dysfunction.
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,Enhanced Methodologies for Investigating the Electrophysiological Characteristics of Endogenous Panls, a human oligodendroglioma cell line that naturally expresses Panx1. We anticipate these refined protocols will significantly contribute to future characterizations of Panx1-based intercellular cell–cell channels across diverse cell types and offer valuable insights into both normal cellular physiology and pathophysiology.
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Book 2024iding known pitfalls..Cutting-edge and comprehensive, .Connexin Hemichannels: Methods and Protocols. is a valuable resource that discusses the importance of HCs as drug targets, and how studying them is essential to identifying newcompounds capable of modulating HC function selectively and specifically.. . .
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Fabio Mammano,Mauricio RetamalIncludes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts
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