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Titlebook: Complex Carbohydrates of Nervous Tissue; Richard U. Margolis,Renée K. Margolis Book 1979 Plenum Press, New York 1979 adenosine.brain.carbo

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书目名称Complex Carbohydrates of Nervous Tissue
编辑Richard U. Margolis,Renée K. Margolis
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图书封面Titlebook: Complex Carbohydrates of Nervous Tissue;  Richard U. Margolis,Renée K. Margolis Book 1979 Plenum Press, New York 1979 adenosine.brain.carbo
描述It is only relatively recently that neurochemists and neurobiologists have shown appreciable interest in the class of macromolecules now generally re­ ferred to as complex carbohydrates, although gangliosides were, of course, first identified and studied in brain. The glycosaminoglycans fell chiefly within the province of connective-tissue biochemists, and earlier informa­ tion concerning the structure and metabolism of glycoproteins was largely limited to the more accessible glycoproteins and oligosaccharides (such as those found in plasma, milk, and urine), or ones which are relatively simple to prepare in a soluble and manageable form. Techniques were later devised for the isolation and purification of tightly bound membrane glycoproteins, where initial studies concentrated mainly on the erythrocyte, for which large amounts of a single cell population are available. Because of the structural complexity of nervous tissue and the large numbers, low concentrations, and membrane-bound form of many of its complex carbohydrates, progress has occurred more slowly in this area.
出版日期Book 1979
关键词adenosine; brain; carbohydrates; cognition; complexity; myelin; nervous system; neurons; tumor
版次1
doihttps://doi.org/10.1007/978-1-4613-2925-1
isbn_softcover978-1-4613-2927-5
isbn_ebook978-1-4613-2925-1
copyrightPlenum Press, New York 1979
The information of publication is updating

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Structure and Distribution of Glycoproteins and Glycosaminoglycans,y composed of disaccharide repeating units of a uronic acid (D-gluc- uronic acid or L-iduronic acid) and a hexosamine (.-acetylglucosamine or .-acetylgalactosamine). In the case of the sulfated glycosaminoglycans, the polysaccharide chains are .-glycosidically linked at their reducing ends to a prot
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Biosynthesis of Glycoproteins,heme in the research of a large number of biochemists and cell biologists, as well as neurochemists. One focal point in these investigations has been the possibility that cell-surface glycoproteins and glycosyltrans- ferases play a role in cell-cell contact relationships (Roseman, 1970). An extensiv
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Biosynthesis of Glycosaminoglycans,ow, however, the use of radioisotopes, the recent development of sensitive, specific colorimetric and enzyme methodologies, and the development of procedures for the isolation of the various cell types and subcellular fractions unique to nervous tissue have prompted renewed interest as to the role o
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Brain Glycosidases,in visceral organs. The nature of subcellular fractions isolated from brain tissue is not well defined. Therefore, assignment of a given glycosidase to a particular organelle has been more difficult than in other tissues. As with glycosidases of other tissues, brain glycosidases exist in multiple fo
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Glycoproteins of the Synapse,of the function of the complex carbohydrates of nerve tissues. Just as snyapses fulfill the crucial role in the establishment, construction, reconstruction, and reinforcement of neuronal pathways of communication, so do glycoproteins subserve the task of establishing and maintaining contact among ce
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Histochemistry of Polyanions in Peripheral Nerve,ith interruptions in the myelin sheath. He also observed that the axon itself was continuous across the “annular constrictions” or nodes, and that only a single Schwann cell nucleus appeared between each pair of nodes along the same fiber. Ranvier was also the first to use heavy metals to stain node
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