Titlebook: Comparative Genomics; Volume 2 Nicholas H. Bergman Book 2007 Humana Press 2007 DNA.Evolution.Genotyp.Microarray.Nucleotide.SNP.Single Nucle

Affirm

https://doi.org/10.1007/978-3-662-43048-4-scale variations in human genomes. This chapter describes methods to analyze copy number alterations in cancer genomes using Affymetrix GeneChip., high-density oligonucleotide microarrays originally developed for large-scale single nucleotide polymorphism (SNP) typing. Combined with the large numbe

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植物群

Der Arzt in der Tuberkulosefürsorgeof genome sequences from closely related strains has uncovered significant differences in gene content, hinting at the dynamic nature of bacterial genomes. The study of these genome dynamics is crucial to leveraging genomic information because the genome sequence of a single bacterial strain may not

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讽刺滑稽戏剧

Nicholas H. BergmanProvides a collection of robust protocols for molecular biologists studying comparative genomics.Each chapter includes detailed instructions for using a particular tool or method and an introduction t

不成比例

配偶

Computational Prediction of Domain Interactionsteracting and/or functionally linked domain pairs from different kinds of input data. Specifically, we will discuss phylogenetic profiling on the level of conserved protein domains on one hand and inference of domain-interactions from observed or predicted protein–protein interactions datasets on th

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Incorruptible

Inference of Gene Function Based on Gene Fusion Eventstion. FusionDB provides a characterization of a large number of gene fusion events at hand of multiple sequence alignments. Orthologous genes are included to yield a comprehensive view of the structure of a gene fusion event. Phylogenetic tree reconstruction is provided to evaluate the history of a

连累

InterPro and InterProScan PROSITE, PRINTS, ProDom, SMART, TIGRFAMs, PIRSF, SUPERFAMILY, Gene3D, and PANTHER. The InterPro database can be searched to retrieve precalculated matches for UniProtKB proteins, or to find additional information on protein families and domains. For completely sequenced genomes, the user can retrie