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Titlebook: Comparative Genomics; Volume 2 Nicholas H. Bergman Book 2007 Humana Press 2007 DNA.Evolution.Genotyp.Microarray.Nucleotide.SNP.Single Nucle

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书目名称Comparative Genomics
副标题Volume 2
编辑Nicholas H. Bergman
视频video
概述Provides a collection of robust protocols for molecular biologists studying comparative genomics.Each chapter includes detailed instructions for using a particular tool or method and an introduction t
丛书名称Methods in Molecular Biology
图书封面Titlebook: Comparative Genomics; Volume 2 Nicholas H. Bergman Book 2007 Humana Press 2007 DNA.Evolution.Genotyp.Microarray.Nucleotide.SNP.Single Nucle
描述.Comparative Genomics, Volume 2, provides a collection of robust protocols for molecular biologists beginning to use comparative genomic analysis tools in a variety of areas. Volume 2 contains the last three of seven sections. In the second volume, the fifth section describes a number of tools for comparative analysis of domain and gene families. These tools are particularly useful for predicting protein function as well as potential protein-protein interactions. In the sixth section, methods for comparing groups of genes and gene order are discussed, as are several tools for analyzing genome evolution. Finally, the seventh section deals with experimental comparative genomics. This section includes methods for comparing gene copy number across an entire genome, comparative genomic hybridization, SNP analysis, as well as genome-wide mapping and typing systems for bacterial genomes. Given the tremendous increase in available biosequence data over the past ten years, Comparative Genomics, Volume 1, is timely, comprehensive, and novel. A companion Volume 1 is also available from Humana Press..
出版日期Book 2007
关键词DNA; Evolution; Genotyp; Microarray; Nucleotide; SNP; Single Nucleotide Polymorphism; genes; hybridization; p
版次1
doihttps://doi.org/10.1007/978-1-59745-515-2
isbn_softcover978-1-61737-933-8
isbn_ebook978-1-59745-515-2Series ISSN 1064-3745 Series E-ISSN 1940-6029
issn_series 1064-3745
copyrightHumana Press 2007
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Die Konflikttheorie feministischer Theoriending, and structural features but also molecular adapters, which mediate the physical interactions between proteins or proteins with other molecules. In addition, two conserved domains can be linked not by physical contact but by a common function like forming a binding pocket..Although a wealth of
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Gerd Sebald,Oliver Dimbath,Michael Heinlein their domains. This allows the detection of strings of domains that are conserved in their content, but not necessarily in their order, that we refer to as . or .. The prominent feature of the method is that it relaxes the rigidity of the orthology criterion and avoids many of the pitfalls of gene
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Gerd Sebald,Oliver Dimbath,Michael Heinlein“guilt by association.” It is assumed that two proteins, which are found to be transcribed by a single transcript in one (or several) genomes are likely to be functionally linked, for example by acting in a same metabolic pathway or by forming a multiprotein complex. This method is of particular int
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https://doi.org/10.1007/978-3-658-41914-1urthermore, discovering and accessing such data is fundamental to biologists. There are, however, databases that perform these tasks. Pfam, a protein families database, is one such database. In this chapter, the use of the web interface to Pfam and the resources provided (annotation, sequence alignm
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Die Zeiten der qualitativen Videoanalysenctional genomics and proteomics technologies for large-scale protein function prediction. However, functional classification is also important for the bench scientist wanting to analyze single or small sets of proteins, or even a single genome. A number of tools are available for sequence classific
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Der Arzt in der Tuberkulosefürsorgein significant variations in gene order and gene content among otherwise closely related organisms. The Mauve genome alignment system can successfully identify such rearrangement and lateral transfer events in comparisons of multiple microbial genomes even under high levels of recombination. This ch
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