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Titlebook: Chronic Myelocytic Leukemia and Interferon; Pathophysiological, Dieter Huhn,Klaus Peter Hellriegel,Norbert Niederl Conference proceedings

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,Differential Regulation of Cell Membrane Receptors for Interferon-γ and -α on Peripheral Blood Cellastic-transformed stem cell [10]. In more than 90% of cases, an indicative reciprocal translocation t(9.22), known as the “Philadelphia chromosome,” is present [39]. The observation that natural interferon-alpha (IFN-α) and fibroblast interferon (IFN-β) caused inhibitory effects on the in vitro grow
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Studies of Interferon as a Regulator on Hematopoietic Stem Cells in Chronic Myelogenous Leukemia,roliferation and accumulation of myeloid cells and their progenitors. Clinically, the disease is divided into three phases: a chronic phase of 3–4 years’ duration followed by an accelerated phase of 3–5 months, and then leading into an acute phase, i. e., blast crisis lasting 2–4 months [1]. During
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