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Titlebook: Chromosome Analysis Protocols; John R. Gosden Book 1994 Humana Press 1994

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发表于 2025-3-21 17:58:12 | 显示全部楼层 |阅读模式
书目名称Chromosome Analysis Protocols
编辑John R. Gosden
视频video
丛书名称Methods in Molecular Biology
图书封面Titlebook: Chromosome Analysis Protocols;  John R. Gosden Book 1994 Humana Press 1994
描述Chromosomes, as the genetic vehicles, provide the basic material for a large proportion of genetic investigations, from the construction of gene maps and models of chromosome organization, to the inves­ tigation of gene function and dysfunction. The study of chromosomes has developed in parallel with other aspects of molecular genetics, beginning with the first preparations of chromosomes from animal cells, through the development of banding techniques, which permitted the unequivocal identification of each chromosome in a karyotype, to the present analytical methods of molecular cytogenetics. Although some of these techniques have been in use for many years, and can be learned relatively easily, most published scientific reports—as a result of pressure on space from editors, and the response to that pressure by authors—contain little in the way of technical detail, and thus are rarely adequate for a researcher hoping to find all the necessary information to embark on a method from scratch. A new user needs not only a detailed description of the methods, but also some help with problem solving and sorting out the difficulties en­ countered in handling any biological system. This wa
出版日期Book 1994
版次1
doihttps://doi.org/10.1385/0896032892
isbn_softcover978-0-89603-243-9
isbn_ebook978-1-59259-516-7Series ISSN 1064-3745 Series E-ISSN 1940-6029
issn_series 1064-3745
copyrightHumana Press 1994
The information of publication is updating

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History of Information Securityports of microdeletions and other abnormalities detected only on extended chromosomes (.). Likewise, in situ hybridization and gene localization techniques are taking advantage of the improved resolution.
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Redesigning the Molecules of Lifeivalent configurations produced. Again, this process of identification being greatly aided by the application of C- or Q- banding techniques. In more recent times, studies have been carried out in which . hybridization of specific probes to MI bivalents has been used (.) and . nick translation proce
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Urban Development in Iran and Tehran, An alternative approach, which will be described here, is to add to the cultured cells some substance that will either be incorporated in the chromosomal DNA or, more usually, bind to the chromosomal DNA, and thereby inhibit condensation of the chromosomes. Such substances may either inhibit the co
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Mitotic Metaphase Chromosome Preparation from Peripheral Blood for High Resolution,ports of microdeletions and other abnormalities detected only on extended chromosomes (.). Likewise, in situ hybridization and gene localization techniques are taking advantage of the improved resolution.
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Electron Microscopic Localization of in Situ Hybrids,oes not require the denaturation step. After hybridization and removal of unhybridized probe, hybrid sites are located by either autoradiography for radioactive probes or via tagging with a visible detector. This chapter focuses on the use of probes labeled in vitro with a variety of nonisotopic tag
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1064-3745 ed description of the methods, but also some help with problem solving and sorting out the difficulties en­ countered in handling any biological system. This wa978-0-89603-243-9978-1-59259-516-7Series ISSN 1064-3745 Series E-ISSN 1940-6029
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