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Titlebook: Chiral Liquid Chromatography; W. J. Lough Book 1989 Chapman & Hall 1989 Enantiomer.chromatography.information.optimization.pharmaceutical.

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Choice of chiral LC systemsould be carried out for LC enantioseparations, not only of the compound in question but also of other closely related structures. A computer search would be ideal, but for those with no access to such facilities reference to the index of this book would be a more than useful substitute.
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Terminological reason maintenance,atographic eluent to effect isomeric separation on an achiral stationary phase, i.e. C. bonded phase. Stereoselective separation of the enantiomeric amino acid pairs results when one of the isomers is differentially retained as the ternary complexes of the metal ion and the chiral ligand.
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The Problem of Monotonicity and the Skeleton scientists for more than a century. The rare instance of a successful separation was often treated either as happenstance or as the success of trial and error. In either event, a systematic approach to the problem was not seen as feasible, except in a few special cases. Clearly, commercial exploitation was unthinkable.
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Representation and management of knowledge,re are no hydroxyls on the interior cavity and it is therefore relatively hydrophobic. Each glucose unit contributes five chiral centres to the molecule, and the 2- hydroxyl groups at the entrance of the cavity are orientated in a clockwise direction. This can best be appreciated by studying Figure 8.2 which shows the geometry of .-cyclodextrin.
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