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Titlebook: Chiral Liquid Chromatography; W. J. Lough Book 1989 Chapman & Hall 1989 Enantiomer.chromatography.information.optimization.pharmaceutical.

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Cyclodextrin inclusion complexationre are no hydroxyls on the interior cavity and it is therefore relatively hydrophobic. Each glucose unit contributes five chiral centres to the molecule, and the 2- hydroxyl groups at the entrance of the cavity are orientated in a clockwise direction. This can best be appreciated by studying Figure 8.2 which shows the geometry of .-cyclodextrin.
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Other direct chiral resolution methodsularized in the future, or else they may provide further useful insights into the whole process of chiral recognition. Most of these other methods are in fact only minor variations on the categories discussed already, but there are also some more novel methods of achieving enantiomeric resolution.
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