| 书目名称 | Chimera Research |
| 副标题 | Methods and Protocol |
| 编辑 | Insoo Hyun,Alejandro De Los Angeles |
| 视频video | |
| 概述 | Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts |
| 丛书名称 | Methods in Molecular Biology |
| 图书封面 |  |
| 描述 | .This volume addresses challenging new questions surrounding stem cell-based chimera research. This book is organized into three parts: Part One provides readers with a summary of different human donor cell types. The chapters in this section discuss ways to evaluate new types of pluripotent stem cells; the derivation of naïve and primed pluripotent stem cells from mouse preimplantation embryos; and the ethical and regulatory complexities of informed consent for the procurement of somatic cells. Part Two discusses methods for generating chimeras. The chapters here look at chick models and human-chick organizer grafts; generating human-pig interspecies chimeras; and techniques for transplanting mouse neural stem cells into a mouse disease model for stroke. Part Three concludes the book with a look at ongoing ethical controversies and new scientific directions. Chapters in this part cover the ethics of crossing the xenobarrier; animal welfare; experimentation with spermatogonial stem cells; and cautious approaches to human-monkey chimera studies to further understand complex human brain disorders. Written in the highly successful .Methods in Molecular Biology. series format, chapters |
| 出版日期 | Book 2019 |
| 关键词 | Pluripotent Stem Cells; Somatic Cells; Whole-organ Transplantation; Xenobarrier; Parabiosis |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-1-4939-9524-0 |
| isbn_softcover | 978-1-4939-9526-4 |
| isbn_ebook | 978-1-4939-9524-0Series ISSN 1064-3745 Series E-ISSN 1940-6029 |
| issn_series | 1064-3745 |
| copyright | Springer Science+Business Media, LLC, part of Springer Nature 2019 |
发表于 2025-3-21 17:01:43
