Titlebook: Chemotherapy of Fungal Diseases; John F. Ryley Book 1990 Springer-Verlag Berlin Heidelberg 1990 Chemotherapeutikum.Mykose.Pilzkrankheit.ch

战役

Clinical Trialsealth Organization 1975; . 1983). We have attempted to place this presentation in perspective by discussing briefly in the first section why clinical trials are used in the development of new antifungal drugs.

鞠躬

Introductione Manchester area (Chap. 13), and my long-standing friend Jack . has highlighted some of the problems he faces in a hospital situation when confronted with the more refractory forms of fungal vaginitis (Chap. 14).

Free-Radical

Alpha-Cells

Hepatic and Endocrine Effects of Azole Antifungal Agents

abysmal

Dirk Dubbers,Hans-Jürgen Stöckmann hovers over his retort planning what to brew up next. His thinking may be directed by analogy with known active structures or by fashionable biochemical pathways, but beyond this the medicinal chemist needs a vision and a feel for the target.

obtuse

Dirk Dubbers,Hans-Jürgen Stöckmannthe relatively simple primary interaction between the drug molecule and a macromolecular structure can drug activity at the molecular level be understood. The increasing complexity of the whole organism, and then the animal model, requires an understanding of many more parameters — including some no

适宜

fastness

Quantum Physics in the Nanoworldcompounds in the body and the different sites of fungal location, some indication of the . spectrum of activity is desirable; e.g. although . is basically susceptible to amphotericin B and systemic infections do show a response to treatment, vaginal ones do not. Other compounds will be basically nar

Cupping

https://doi.org/10.1007/978-3-642-31238-0nd regulatory procedures burgeoned in the hope of avoiding a similar situation in the future. Sally Eardley, a colleague from ICI, has written a delightful chapter (11) chronicling regulatory developments over the past 3500 years. Although she has had no experience with antifungal drugs, I find her

PRO