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Titlebook: Chemotherapy of Fungal Diseases; John F. Ryley Book 1990 Springer-Verlag Berlin Heidelberg 1990 Chemotherapeutikum.Mykose.Pilzkrankheit.ch

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Dirk Dubbers,Hans-Jürgen Stöckmannbiological experimentation and ultimately for therapeutic or prophylactic use in disease. In the antifungal area, the complexity of drug-fungal interactions and the intensity of the drug effect depend to a large extent on the concentration of drug in the active biophase (e.g. cell membrane), whereas
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Dirk Dubbers,Hans-Jürgen Stöckmanned in major increases in serious fungal infections. Amphotericin B remains the standard treatment of systemic mycoses, but its use is limited by severe toxic properties which make it imperative that safer and more effective therapies be found. Natural products, especially antibiotics from fermentati
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Dirk Dubbers,Hans-Jürgen Stöckmanndidate substances for screening may include chemical compounds selected at random or according to particular structural features from an existing chemical collection, compounds designed and synthesised specifically by project chemists and broths or extracts of natural product origin. The purpose of
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Quantum Physics in the Nanoworldthat they should be able to cope with large numbers of compounds in restricted quantity. Although topical activity may be achievable in a new compound, a profusion of topical antifungals of differing chemical types is already available. As the current medical need is rather for safer and more effect
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Quantum Physics in the Nanoworldication of the concepts of pharmacokinetics to the discovery and development of better therapeutic agents, particularly within the pharmaceutical industry, is growing rapidly. There are several aspects of this process which are particularly important in the development of antimicrobial agents. Thus,
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