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Titlebook: Checkpoint Controls and Cancer; Volume 1: Reviews an Axel H. Schönthal Book 2004 Humana Press 2004

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Cost of Goods Sold and Inventory Model,ng and staining of tissues with an antibody to phosphorylated histone H3 to measure the mitotic index. These methods should be useful in identifying potential mutants that are unable to regulate mitosis following DNA damage.
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Analyzing the Spindle Checkpoint in Yeast and Frogs single kinetochore can inhibit cell cycle progression in the absence of proper spindle attachment or tension from bipolar orientation. Recent advances have shed light on how the kinetochore measures these situations, transduces a signal, and inhibits the entry into anaphase.
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Establishment of a Cell-Free System to Study the Activation of Chk2eat germ extract in vitro transcription/translation system is inactive and can be activated by incubating with a rabbit reticulocyte lysate. This method will be useful for identification of cofactors required for activation of Chk2.
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