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Titlebook: Checkpoint Controls and Cancer; Volume 1: Reviews an Axel H. Schönthal Book 2004 Humana Press 2004

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Control of Mitotic Entry After DNA Damage in ,lticellular model organism, ., are described here. These include the collection of embryos and larvae, irradiation with x-rays to damage DNA, and fixing and staining of tissues with an antibody to phosphorylated histone H3 to measure the mitotic index. These methods should be useful in identifying p
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Methods for Analyzing Checkpoint Responses in ,or elicit programmed cell death (apoptosis) of affected cells. The . germ line was recently established as a model system to study these processes in a genetically tractable, multicellular organism. The utility of this system was revealed by the finding that upon treatment with genotoxic agents, pre
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Axel H. SchönthalIncludes supplementary material:
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Methods in Molecular Biologyhttp://image.papertrans.cn/c/image/224210.jpg
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Analyzing Checkpoint Controls in Human Skinowing exposure to ultraviolet radiation (UVR). This model affords the opportunity to manipulate the growth and nutrient conditions, and to perform detailed biochemical and immunohistochemical analysis of skin cells in their normal epidermal layer microenvironment. The use of this model is described in this chapter.
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Checkpoint Controls and Cancer978-1-59259-788-8Series ISSN 1064-3745 Series E-ISSN 1940-6029
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Cost of Product Development Model,owing exposure to ultraviolet radiation (UVR). This model affords the opportunity to manipulate the growth and nutrient conditions, and to perform detailed biochemical and immunohistochemical analysis of skin cells in their normal epidermal layer microenvironment. The use of this model is described in this chapter.
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https://doi.org/10.1007/978-1-4302-0580-7n is coordinated with cell growth, while the initiation of DNA synthesis (S phase) is precisely ordered to prevent inappropriate amplification of the DNA that may cause genome instability. To ensure that these fundamental requirements of cell division are met, cells have developed a surveillance mec
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