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Titlebook: Central Nervous System Leukemia; Prevention and Treat Renato Mastrangelo,David G. Poplack,Riccardo Ricca Book 1983 Martinus Nijhoff Publish

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Evaluation of Adverse Sequelae of Central Nervous System Prophylaxis in Acute Lymphoblastic Leukemiharacterize the adverse sequelae associated with CNS prophylaxis (1–3). The present report will summarize the findings of these studies and discuss their implications for the treatment of the patient with ALL.
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Book 1983r 50% of children with this disease will be alive and free of their disease at least 5 years from the time of their initial diagnosis. Although a number of factors have contributed to this improvement, perhaps none has been as important as the institution of central nervous system preventive therapy
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Siegfried Nolting,Hans Christian Kortingto explore the possibility of utilizing alternative approaches with currently available chemotherapy. In this report we will discuss studies which we have undertaken with two currently available chemotherapeutic agents, cytosine arabinoside and L-asparaginase, in an attempt to define new approaches to the treatment of CNS leukemia.
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Treatment of Meningeal Leukemia: Investigation of New Approaches with Conventional Agents,to explore the possibility of utilizing alternative approaches with currently available chemotherapy. In this report we will discuss studies which we have undertaken with two currently available chemotherapeutic agents, cytosine arabinoside and L-asparaginase, in an attempt to define new approaches to the treatment of CNS leukemia.
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https://doi.org/10.1007/978-3-642-74678-9hese problems by examining a) the anatomy of the leptomeninges as it pertains to CNS leukemia, b) the sequence of events occurring during the histopathogenesis of meningeal leukemia, and c) the histological sequelae and their resultant clinical manifestations.
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, Oncogenes in Chemical Carcinogenesis,rapy, based on the CNS sanctuary theory, has been widely used and the results obtained with this approach have been discussed by D’Angio (2), Mauer (3), Bleyer (4) and Hardisty (5) elsewhere in this volume.
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Die Onychomykose-Therapie in der Praxis,dence for the efficacy of such treatment (1, 2), all patients entered to subsequent trials have received some form of CNS prophylaxis. This report compares the results to date of the various prophylactic regimes used in UKALL trials I–V, to which patients were entered between 1970 and 1979.
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