Titlebook: Cell Death Signaling in Cancer Biology and Treatment; Daniel E. Johnson Book 2013 Springer Science+Business Media New York 2013 Cancer.Can

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Book 2013ic modifications, DNA repair pathways, and protein chaperones, as a means of provoking tumor cell death. Finally, the development and application of novel agents and approaches for targeting specific components of cell death signaling pathways and machinery will be reviewed.

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Leading Small Molecule Inhibitors of Anti-Apoptotic Bcl-2 Family Members,opment and application of three small molecule inhibitors (ABT-737, ABT-263, GX15-070), with a particular emphasis on progress that has been made in the evaluation of these compounds in preclinical in vivo models and clinical trials.

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Book 2013 and Treatment. is to describe state-of-the-art approaches and future opportunities for achieving this goal by targeting mechanisms and pathways that regulate cancer cell death. In this book, molecular defects in cell death signaling that characterize cancer cells, including dysregulation of cell de

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2625-2902 or cell death. Finally, the development and application of novel agents and approaches for targeting specific components of cell death signaling pathways and machinery will be reviewed.978-1-4939-0107-4978-1-4614-5847-0Series ISSN 2625-2902 Series E-ISSN 2625-2899

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Assessing IEQ Performance in BuildingsThis has become highly relevant as it is suggested that most cancer cells are likely to be defective in some aspect of DNA repair. Herein, we describe the molecular pathways that participate in the repair of DNA damage induced by radiation- and chemotherapeutics and discuss strategies that are being

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Acids and Additives Used in Acidizingable target for cancer treatment. This idea has been validated from benchtop to bedside. In 2003, the first proteasome inhibitor anticancer drug, bortezomib, was approved in the United States for the treatment of multiple myeloma and mantle cell lymphoma. While bortezomib achieved great success in c

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Arrivals, Departures and Returnsle environment for the generation of anti-tumor immunity. Activation of immune-mediated tumor cell death by chemotherapy opens the door to the possibility of novel treatment strategies combining standard chemotherapy with immunotherapy agents aimed at enhancing such responses. Preclinical studies an

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