| 书目名称 | Cell Death Signaling in Cancer Biology and Treatment |
| 编辑 | Daniel E. Johnson |
| 视频video | |
| 概述 | Describes state-of-the-art approaches and future opportunities for selective and efficient killing of tumor cells.Discusses preclinical and clinical approaches.Features development and application of |
| 丛书名称 | Cell Death in Biology and Diseases |
| 图书封面 |  |
| 描述 | A key goal in the treatment of cancer is to achieve selective and efficient killing of tumor cells. The aim of .Cell Death Signaling in Cancer Biology and Treatment. is to describe state-of-the-art approaches and future opportunities for achieving this goal by targeting mechanisms and pathways that regulate cancer cell death. In this book, molecular defects in cell death signaling that characterize cancer cells, including dysregulation of cell death due to overexpression/hyperactivation of oncoproteins, as well as the loss of tumor suppressor proteins will be described. The potential for targeting microRNAs will be discussed. Multiple chapters will describe preclinical and clinical approaches that are currently being used to target epigenetic modifications, DNA repair pathways, and protein chaperones, as a means of provoking tumor cell death. Finally, the development and application of novel agents and approaches for targeting specific components of cell death signaling pathways and machinery will be reviewed. |
| 出版日期 | Book 2013 |
| 关键词 | Cancer; Cancer Biology; Cancer Therapy; Cell Death; Johnson; Oncogenesis; Apoptosis |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-1-4614-5847-0 |
| isbn_softcover | 978-1-4939-0107-4 |
| isbn_ebook | 978-1-4614-5847-0Series ISSN 2625-2902 Series E-ISSN 2625-2899 |
| issn_series | 2625-2902 |
| copyright | Springer Science+Business Media New York 2013 |
发表于 2025-3-21 20:05:57
