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Titlebook: Cardiac Energy Metabolism in Health and Disease; Gary D. Lopaschuk,Naranjan S. Dhalla Book 2014 Springer Science+Business Media New York 2

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https://doi.org/10.1007/0-387-36620-2of the intracellular cycling of CD36 underlies various cardiac metabolic diseases. As a result, the mechanism and regulation of myocardial glucose uptake by GLUT4 cycling and of fatty acid uptake by CD36 cycling are very similar. Likely, manipulation of the presence and/or activity of substrate tran
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Local Weighting of Functional Variablesummarizes our current understanding of the perturbations in the gene regulatory pathways that occur during the development of heart failure. An appreciation of the role this regulatory circuitry serves in the regulation of cardiac energy metabolism may guide the development of novel therapeutic targ
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Nonparametric Functional Data Analysisanelles with high concentrations of Ca.. These observations support the view that mitochondrial dysfunction with respect to energy production due to I/R injury, occurs as a result of oxidative stress and intracellular Ca.-overload. It is also evident that mitochondrial alterations in the I/R hearts
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Ricardo Fraiman,Gonzalo Perez Iribarrench from one substrate to another according to substrate availability, nutritional status, and exercise level. Paradoxically, during prolonged and severe ischemia the myocardium continues to derive most of its energy (50–70 %) from β-oxidation, despite a high rate of lactate production. At this stage
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