Titlebook: Cardiac Energy Metabolism in Health and Disease; Gary D. Lopaschuk,Naranjan S. Dhalla Book 2014 Springer Science+Business Media New York 2

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Nonparametric Functional Data Analysisvelopment of pathological cardiac hypertrophy, a significant remodeling of metabolic pathways leads to a disruption in energy homeostasis, which contributes to the eventual heart failure. These changes include a shift of substrate preference from fatty acids to glucose, a reduction in the overall ox

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Miklós Csörgő,Lajos Horváth,Paul Deheuvelsits associated dyslipidemia negatively affect the myocardium and lead to cardiac dysfunction. Current dogma suggests that obesity-associated dyslipidemia increases fatty acid delivery to the heart, which contributes to both excessive fatty acid uptake and subsequent fatty acid oxidation rates that u

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Role of Lipoprotein Lipase in Fatty Acid Delivery to the Heartprotein lipase (LPL), the enzyme responsible for providing fat to the hearts. Either exaggeration or reduction in its activity following diabetes could lead to heart dysfunction. The objective of this article is to describe the biology of LPL during diabetes. By gaining more insight into the mechani

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Control of Myocardial Fatty Acid Uptakeof the intracellular cycling of CD36 underlies various cardiac metabolic diseases. As a result, the mechanism and regulation of myocardial glucose uptake by GLUT4 cycling and of fatty acid uptake by CD36 cycling are very similar. Likely, manipulation of the presence and/or activity of substrate tran